With Incidental Observations on Certain Manifestations in Macacus Rhesus Monkeys on a Scorbutic

With the Aycock strain of the virus and the intracerebral route of inoculation, Jungeblut (1, 2) found that 77 of 243 (31.3 per cent) vitamin C-treated monkeys escaped paralysis, as compared with only seven of 136 (5.2 per cent) untreated animals. When synthetic vitamin C was used, no significant effect was obtained since only eleven of 101, or 10.2 per cent, failed to develop paralysis. With the M.V. virus (special strain used exclusively for nasal instillation for several years and obtained from the writer) instilled intranasaUy Jungeblut (2) reported that only one of twenty monkeys treated with 5 to 25 nag. of natural vitamin C daily (optimum dose in intracerebral experiments) showed no paralysis, while among ten animals treated with 50 to 100 nag. daily nine escaped paralysis; fifteen untreated monkeys all became paralyzed.